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The Ross-Yacoub procedure (or pulmonary autograft) is a cardiac surgery operation where a diseased aortic valve is replaced with the person's own pulmonary valve.A pulmonary allograft (valve taken from a cadaver) is then used to replace the patient's own pulmonary valve. Colposcopy is a way to get a close-up look at your cervix. It’s a quick and easy way to find cell changes in your cervix that may turn into cancer. A colposcopy is a type of cervical cancer test. It lets your doctor or nurse get a close-up look at your cervix — the opening to your uterus. Plaquemines Parish Sheriff's Office Jail Roster: Click to register anonymously to be notified upon any changes in this offender's custody status. Millions of real salary data collected from government and companies - annual starting salaries, average salaries, payscale by company, job title, and city.

The Ross-Yacoub procedure (or pulmonary autograft) is a cardiac surgery operation where a diseased aortic valve is replaced with the person's own pulmonary valve. A pulmonary allograft (valve taken from a cadaver) is then used to replace the patient's own pulmonary valve. Pulmonary autograft replacement of the aortic valve is the operation of choice in infants and children, but its use in adults remains controversial.^[1]

History[edit]

The Ross-Yacoub procedure is named after Dr. Donald Ross and Dr. Magdi Yacoub — a pioneer in cardiac surgery in the UK — who proposed the procedure in 1962^[2] and first performed it in 1967.

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Advantages and disadvantages[edit]

The pros and cons of this procedure are:^{[citation needed]}

Advantages[edit]

• Freedom from thromboembolism without the need for anticoagulation.
• The valve grows as the patient grows (i.e., children).
• Favourable hemodynamics.
• No foreign material present in the valve.

Disadvantages[edit]

• Single-valve disease (aortic) treated with a two-valve procedure (aortic and pulmonary).

Pulmonary valve replacement[edit]

One of the main objections to the Ross-Yacoub procedure is the genesis of pulmonary valve disease in addition to aortic valve disease. Proponents have argued that biological valves implanted in the pulmonary position would be slow to develop dysfunction, and any dysfunction would be well tolerated due to the lower pressures in the right side of the heart. Survival of homografts in the pulmonary position is good (20-year freedom from reoperation of 80%), and homograft dysfunction is infrequently implicated in the observed morbidity and mortality.^[3]

Homografts (aortic or pulmonary) should be the replacement of choice; no other valve performed as well in the pulmonary position. Many homograft valves are sterilized with ethylene oxide or irradiation—methods recognized to have deleterious effects on valve performance. The results of the pulmonary autograft procedure are likely to be superior with the use of fresh homograft valves.^[3] Today, cryopreservation is the method of choice for homograft preservation.^{[citation needed]}

See also[edit]

References[edit]

1. ^Yacoub M, Klieverik L, Melina G, Edwards S, Sarathchandra P, Bogers A, Squarcia U, Sani G, van Herwerden L, Takkenberg J (2006). 'An evaluation of the Ross operation in adults'. J Heart Valve Dis. 15 (4): 531–9. PMID16901050.
2. ^Ross D (1962). 'Homograft replacement of the aortic valve'. Lancet. 2 (7254): 487. doi:10.1016/S0140-6736(62)90345-8. PMID14494158.
3. ^ ^abChambers J, Somerville J, Stone S, Ross D (1997). 'Pulmonary autograft procedure for aortic valve disease: long-term results of the pioneer series'. Circulation. 96 (7): 2206–14. doi:10.1161/01.cir.96.7.2206. PMID9337191.

External links[edit]

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• Cardiac Surgery in the Adult - Pulmonary autograft